Isolation of flavonoid extract from Georgian Citrus sinensis peel and some of its properties

Author: Nika Atanelov
Co-authors: Nana Koshoridze, Giorgi Burjanadze, Giorgi Kuprava, Nino Arutinashvili
Keywords: Flavonoids, Psycho-emotional stress, antioxidant systems, Energy metabolism
Annotation:

A method for isolation of polyphenol extract with significant amounts of flavonoid compounds (GOF) from precocious Georgian Citrus sinensis peel (Citrus sinensis (L.) Osbeck ,,Seike Navel”, form N26) was established by multistage process based on producing water-associated fraction (WAF). Recent study describes the impact of GOF on altered metabolism patterns of cardiac muscle cells induced by psycho-emotional stress. Markedly, GOF-treated animals show positive changes in certain antioxidant enzymes (SOD, catalase) activity and normalization of lipid peroxidaiton, whereas the concentration of Ca2+ and nitric oxide are approximated to the control value.